Pharmacometrics:From Data to Dose
A practical text on turning pharmacokinetic and pharmacodynamic data into a defensible dose — written for people who will have to justify the number.
Malek Okour, PhD
On the curve at t = 0, riding it from the side: up the absorption limb, over Cmax, down the tail
Each chapter is built from public sources and worked examples, with its limitations stated explicitly.
Blue is what a chapter draws on; amber is the worked material; green is what it does not claim.
Two ways in
Where you should start
For the practitioner
You already fit models. Go to the chapter that owns the question in front of you, and read how its assumptions and limits are argued.
For the newcomer
You have the pharmacology but not the modeling. Start with what pharmacometrics is for and how to read a report, then work forward.
Pick a path
Reading shortcuts
V5 working draft. 83 chapter texts across 12 parts are drafted; review is ongoing. A written draft is not an accepted or published text.
Have feedback on this draft? Include the book title and edition, the chapter or heading, and the exact passage.
Contact MalekCompanion reports are not included in this web draft.
